Using Epigenomics and Genomics to Better Understand the Roles and Mechanisms of Environmental Determinants of Breast Cancer

Genetic and environmental causes of variation in epigenetic aging across the lifespan

S Li, TL Nguyen, EM Wong, PA Dugué, GS Dite, NJ Armstrong, JM Craig, KA Mather, PS Sachdev, R Saffery, J Sung, Q Tan, A Thalamuthu, RL Milne, GG Giles, MC Southey, JL Hopper

2020-12-01

Background: DNA methylation-based biological age (DNAm age) is an important biomarker for adult health. Studies in specific age ra..

DNA methylation-based biological age, genome-wide average DNA methylation, and conventional breast cancer risk factors

M Chen, EM Wong, TL Nguyen, GS Dite, J Stone, PA Dugué, GG Giles, MC Southey, RL Milne, JL Hopper, S Li

2019-12-01

DNA methylation-based biological age (DNAm age), as well as genome-wide average DNA methylation, have been reported to predict bre..

Genome-wide association study of peripheral blood DNA methylation and conventional mammographic density measures

S Li, PA Dugué, L Baglietto, G Severi, EM Wong, TL Nguyen, J Stone, DR English, MC Southey, GG Giles, JL Hopper, RL Milne

2019-10-01

Age- and body mass index (BMI)-adjusted mammographic density is one of the strongest breast cancer risk factors. DNA methylation i..

Causal effect of smoking on DNA methylation in peripheral blood: A twin and family study

S Li, EM Wong, M Bui, TL Nguyen, JHE Joo, J Stone, GS Dite, GG Giles, R Saffery, MC Southey, JL Hopper

2018-02-09

Background: Smoking has been reported to be associated with peripheral blood DNA methylation, but the causal aspects of the associ..